Difference between revisions of "Rivers"

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== Project summary ==
 
== Project summary ==
  
* '''Resistance of Influenza Viruses in Environmental Reservoirs and Systems (RIVERS) - project No SSPE-CT-2006-44405, maintained within the 6th Framework Programme'''
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'''Resistance of Influenza Viruses in Environmental Reservoirs and Systems (RIVERS) - project No SSPE-CT-2006-44405, maintained within the 6th Framework Programme'''
  
The surge of the global avian influenza epizootic caused by the genotype Z highly pathogenic avian influenza virus (HPAIV) has posed numerous questions, in particular to risk managers and policy makers. Scientific knowledge is thin on many aspects of the ecology and environmental properties of HPAIVs, in particular H5N1. Virus survival, a key element in control strategies, is an illustration of this paucity of knowledge. Data from the literature on AIV survival are rather limited, often very old an sometimes not confirmed from one study to another or even contradictory. The results obtained with various sub-types of influenza A viruses cannot be extrapolated to the current A(H5N1) viruses before a careful consideration. Further, few information is provided regarding the survival of influenza viruses in the air and on surfaces.
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The surge of the global avian influenza epizootic caused by the genotype A highly pathogenic avian influenza virus (HPAIV) has posed numerous questions, in particular to risk managers and policy makers. Scientific knowledge is thin on many aspects of the ecology and environmental properties of HPAIVs, in particular H5N1. Virus survival, a key element in control strategies, is an illustration of this paucity of knowledge. Data from the literature on AIV survival are rather limited, often very old an sometimes not confirmed from one study to another or even contradictory. The results obtained with various sub-types of influenza A viruses cannot be extrapolated to the current A(H5N1) viruses before a careful consideration. Further, few information is provided regarding the survival of influenza viruses in the air and on surfaces.
  
Under this project, 9 institutions directly involved in AIV studies, of which 3 from Asian countries, have joined forces in order to investigate the prevention and control of influenza outbreaks in animal population at present and at time of restocking. More precisely, the objectives are:
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Under this project, 9 institutions directly involved in AIV studies, of which 3 from Asian countries, have joined forces in order to investigate the prevention and control of influenza outbreaks in animal population at present and at time of restocking. More precisely, the objectives are:
 
* to understand the basis of virus survival from a virological point of view,
 
* to understand the basis of virus survival from a virological point of view,
 
* to understand the impact of physical and chemical elements on virus survival,
 
* to understand the impact of physical and chemical elements on virus survival,
 
* to evaluate the role of environmental reservoirs,
 
* to evaluate the role of environmental reservoirs,
 
* to propose general protocols for the concentration and detection of AIVs in waters, including waste waters, and in different matrices including food,
 
* to propose general protocols for the concentration and detection of AIVs in waters, including waste waters, and in different matrices including food,
* to provide a database together with analytical tools to allow the generation of evidence based guidelines for the prevention and control of influenza outbreaks in animal and human populations, especially at times of restocking.
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* to provide a database together with analytical tools to allow the generation of evidence based guidelines for the prevention and control of influenza outbreaks in animal and human populations, especially at times of restocking.
  
 
== Participating Institutes ==
 
== Participating Institutes ==
  
  
# '''Institut Pasteur de Paris''' (koordynator projektu) – 25-28 rue du Docteur Roux, 75015, Paris, France
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# '''Institut Pasteur de Paris''' (project's coordinator) – 25-28 rue du Docteur Roux, 75015, Paris, France
 
# '''Cantacuzino National Institute of Research and Development Microbiology and Immunology''' – Splaiul Independentei 103, district 5, Bucuresti, 1-525 050096, Romania
 
# '''Cantacuzino National Institute of Research and Development Microbiology and Immunology''' – Splaiul Independentei 103, district 5, Bucuresti, 1-525 050096, Romania
 
# '''The Stephan Angeloff Institute of Microbiology''' – Acad. G. Bonchev Str. 26, Sofia, 1113, Bulgaria
 
# '''The Stephan Angeloff Institute of Microbiology''' – Acad. G. Bonchev Str. 26, Sofia, 1113, Bulgaria
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# '''Centre de Coopération Internationale en Recherche Agronomique pour le Développement (CIRAD)''' – 42 rue Scheiffer, 75116 Paris, France
 
# '''Centre de Coopération Internationale en Recherche Agronomique pour le Développement (CIRAD)''' – 42 rue Scheiffer, 75116 Paris, France
 
# '''Institut Pasteur de Lille''' – 1 rue du Professeur Calmette, 59019, Lille, France
 
# '''Institut Pasteur de Lille''' – 1 rue du Professeur Calmette, 59019, Lille, France
# '''Interdyscyplinarne Centrum Modelowania Matematycznego i Komputerowego Uniwersytetu Warszawskiego''' – Pawińskiego 5A, Blok D, Warszawa PL-02-106, Poland
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# '''Interdisciplinary Centre for Mathematical and Computational Modelling, University of Warsaw''' – Pawińskiego 5A, Bld. D, Warsaw PL-02-106, Poland
 
# '''Wuhan Institute of Virology, Chinese Academy of Sciences''' – Xiaohongshan 44, Wuhan, 430071, China
 
# '''Wuhan Institute of Virology, Chinese Academy of Sciences''' – Xiaohongshan 44, Wuhan, 430071, China
  
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== Project objectives ==
 
== Project objectives ==
 
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== Workpackages ==
 
== Workpackages ==
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'''WPG I''' – Przetrwanie wirusa ptasiej grypy w środowiskach i zbiornikach wodnych
 
WP0: Podstawy molekularne dla przetrwania i mutacji wirusa, w szczególności badania tzw. „bio-equivalence” w odniesieniu do możliwości stosowania metod wypracowanych dla identyfikacji i wykrywalności wirusa grypy typu A(H1N1) dla analogicznych sytuacji w odniesieniu do wirusa A(H5N1).
 
WP1: Koncentracja, identyfikacja i szacowanie ilościowe występowania wirusa grypy w zbiornikach wodnych, w terenach podmokłych i w faunie wodnej.
 
WP2: Obserwacja wirusa ptasiej grypy w środowisku naturalnym
 
WP3: Obserwacja koncentracji i przetrwania wirusa ptasiej grypy w warunkach eksperymentalnych
 
WP4: Wpływ związków występujących w wodzie na przetrwanie wirusa AIV.
 
'''WPG II''' –  Przetrwanie wirusa ptasiej grypy w powietrzu i na powierzchniach
 
WP5: Wpływ czynników atmosferycznych na przetrwanie wirusa
 
WP6: Żywotność wirusa w otoczeniu gospodarstw wiejskich.
 
WP7: Wpływ związków w występujących powietrzu i na powierzchniach gruntowych na przetrwanie wirusa
 
WP8: Określenie wpływu wybranych parametrów procesu produkcji spożywczej na przetrwanie wirusa.
 
  
'''WPG III''' Modelowanie teoretyczne wraz z wnioskami i rekomendacjami
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* '''WPG I''': Survival of influenza viruses in waters and aquatic biological systems
  WP9: Modelowanie dynamiki populacji wirusa grypy w naturalnych zbiornikach wodnych, w powietrzu oraz na powierzchniach, ze szczególnym uwzględnieniem gleby, akwenów wodnych i habitatów naturalnych.
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* '''WPG II''': Survival of avian influenza viruses in air and surfaces
 
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* '''WPG III''': Modeling and recommendations
'''WPG IV''' – Wykorzystanie i rozpowszechnienie wyników. Zarządzanie projektem.
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* '''WPG IV''': Exploitation and dissemination of the results, Project management
WP10: Wnioski i rekomendacje dla zapobieganiu, kontroli i zarządzania kryzysowego w razie wybuchów epidemii ptasiej grypy wśród ptactwa dzikiego i hodowlanego, potencjalnie prowadzących do powstania warunków dla pandemii porównywalnej z wysoce śmiertelnym epizodem tzw. grypy hiszpanki w latach 1918-1919.
 
WP11: Zarządzanie projektem.
 
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== Planned results ==
 
== Planned results ==
 
  
 
== Social dynamics simulations ==
 
== Social dynamics simulations ==
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== ICM in RIVERS ==
  
== ICM in RIVERS, popularisation ==
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ICM coordinates the Work Programme III, in particular the Workpackage 9 - ''Modeling of virus survival and concentration in natural water reservoirs and soiled surfaces''.

Latest revision as of 17:33, 10 May 2018

Rivers
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Project summary

Resistance of Influenza Viruses in Environmental Reservoirs and Systems (RIVERS) - project No SSPE-CT-2006-44405, maintained within the 6th Framework Programme

The surge of the global avian influenza epizootic caused by the genotype A highly pathogenic avian influenza virus (HPAIV) has posed numerous questions, in particular to risk managers and policy makers. Scientific knowledge is thin on many aspects of the ecology and environmental properties of HPAIVs, in particular H5N1. Virus survival, a key element in control strategies, is an illustration of this paucity of knowledge. Data from the literature on AIV survival are rather limited, often very old an sometimes not confirmed from one study to another or even contradictory. The results obtained with various sub-types of influenza A viruses cannot be extrapolated to the current A(H5N1) viruses before a careful consideration. Further, few information is provided regarding the survival of influenza viruses in the air and on surfaces.

Under this project, 9 institutions directly involved in AIV studies, of which 3 from Asian countries, have joined forces in order to investigate the prevention and control of influenza outbreaks in animal population at present and at time of restocking. More precisely, the objectives are:

  • to understand the basis of virus survival from a virological point of view,
  • to understand the impact of physical and chemical elements on virus survival,
  • to evaluate the role of environmental reservoirs,
  • to propose general protocols for the concentration and detection of AIVs in waters, including waste waters, and in different matrices including food,
  • to provide a database together with analytical tools to allow the generation of evidence based guidelines for the prevention and control of influenza outbreaks in animal and human populations, especially at times of restocking.

Participating Institutes

  1. Institut Pasteur de Paris (project's coordinator) – 25-28 rue du Docteur Roux, 75015, Paris, France
  2. Cantacuzino National Institute of Research and Development Microbiology and Immunology – Splaiul Independentei 103, district 5, Bucuresti, 1-525 050096, Romania
  3. The Stephan Angeloff Institute of Microbiology – Acad. G. Bonchev Str. 26, Sofia, 1113, Bulgaria
  4. Institut Pasteur du Cambodge – 5, Monivong Boulevard, Phnom Penh, 983, Cambodia
  5. Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences – Pasteur Institute of Shanghai – 225 South Chong Qing Rd., #2, Shanghai, 200025, China
  6. Centre de Coopération Internationale en Recherche Agronomique pour le Développement (CIRAD) – 42 rue Scheiffer, 75116 Paris, France
  7. Institut Pasteur de Lille – 1 rue du Professeur Calmette, 59019, Lille, France
  8. Interdisciplinary Centre for Mathematical and Computational Modelling, University of Warsaw – Pawińskiego 5A, Bld. D, Warsaw PL-02-106, Poland
  9. Wuhan Institute of Virology, Chinese Academy of Sciences – Xiaohongshan 44, Wuhan, 430071, China


Workpackages

  • WPG I: Survival of influenza viruses in waters and aquatic biological systems
  • WPG II: Survival of avian influenza viruses in air and surfaces
  • WPG III: Modeling and recommendations
  • WPG IV: Exploitation and dissemination of the results, Project management


ICM in RIVERS

ICM coordinates the Work Programme III, in particular the Workpackage 9 - Modeling of virus survival and concentration in natural water reservoirs and soiled surfaces.